METHODS: Resting tension, developed tension, diastolic time, force-frequency relationship were measured during isolated papillary muscle perfusion. 方法:应用离体乳头肌灌流的方法观测KB-R7943对正常大鼠及高血压心肌肥厚大鼠乳头肌静息张力、主动张力、心肌舒张时间、张力&频率关系的影响;
Results: Bile noticeably reduced the resting tension of longitudinal muscle ( LM) strips of duodenum and decreased mean contractile amplitude and contractile frequency of duodenum muscle strips, which was dose dependent. 结果:胆汁显著降低兔十二指肠肌条张力,减小其收缩波平均振幅及收缩频率,并有剂量依赖关系。
Result: Dark plum dose dependently increased the resting tension and the contractile frequency. 异搏定可部分阻断乌梅增高肌条张力和增加收缩频率的作用。
But when he basic tension was below the resting tension, the frequency of the autorhythmicity decreased significantly until it disappears. Though increased the basic tension at that time, the autorhythmicity does not appear again. 但当基础张力降至静息张力以下时,自律性频率明显降低,直至消失。此时再回升张力,自律性频率也不能回复。